Immune-mediated adverse events (imAEs) are indeed one of the limiting factors for development of cancer treatments, resulting in patients needing to be nursed back to health in carefully monitored environments. imAEs are also called immune-related adverse events (irAEs) and measuring the immune repertoire may help indicate if a patient will have a greater propensity for them. Identifying methods to monitor and speed up the recovery of the immune repertoire would also be beneficial.Īccurately determining the immune repertoire is challenging on several fronts.
High enough throughput is required to be able to identify all the genetic rearrangements that make up the immune repertoire. High sensitivity is also required to detect the rare clones within the repertoire. Open source web and Mac application Cryptocat is now available on iOS. Designed to allow secure online chatting, the app encrypts chat messages to allow users to have single and group conversations that are secure and unable to be intercepted or monitored.Įveryone's favourite privacy-loving cat is now on iPhone! Get an encrypted cat in your pocket, have private chats with friends any time.Įasily have group conversations with your friends without fearing monitoring or interception. Cryptocat is free, open chat that aims to provide an open, accessible Instant Messaging environment with a transparent layer of encryption that's easy to use. Unlike other secure chat apps, including Confide, Cryptocat does not require usernames, email addresses, or accounts to use, with users entering a one-time nickname to chat. There are also no buddy lists or account history, making conversations ephemeral.Īccording to the developers, Cryptocat is a native iPhone application that uses iOS APIs rather than web cryptography, but it is designed to work seamlessly with other Cryptocat clients. Along with an iOS app, Cryptocat is also available for the Mac and as a browser extension for Chrome, Firefox, and Safari.Ĭryptocat was originally announced for iOS in December, but the app was initially rejected by Apple, a decision that has since been reversed. According to the app's developer, who spoke to The Verge, the issues with Apple have been resolved. "There was some very important help given by the Electronic Frontier Foundation, and we ended up scheduling a conversation with Apple, and after a while Apple was very gracious and understanding,” he said.